Adam (Leigh Whannell) and Dr. Lawrence Gordon (Cary Elwes) wake up chained to pipes at opposite ends of a dirty utility room. They soon learn that they have become the victims of the Jigsaw, a serial killer who devises intricate situations to get his victims to kill each other. Pitted against the clock and each other, the two must work to outwit their captor and save Gordon's family, who have been taken hostage by the killer.